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OCR: s several cluding Ketoconazole, an antifungal drug, inhib cytochrome P450- dependent enzymes, i rtisol es). It is, 11 p-hydroxylase, thus interfering with c synthesis (an unwanted effect in most c Cushing's however, being used increasingly to tre Atic syndrome, precocious puberty, and pros carcinoma. See also: herapy · Cushing's Syndrome - Ketoconazole